Reprezentacja Ja u wysokofunkcjonujących osób z autyzmem – przegląd badań z wykorzystaniem metod neuroobrazowania mózgu

Hanna B. Cygan


Self-Representation in High-Functioning Autism – Review of Neuroimaging Experiments

Development of self-representation is vitally important for internalizing typical behavior and for building interpersonal relationships. Taking into account the neuronal underpinnings of cognitive functions, symptoms of autism spectrum disorders (ASD) have been related to impairments of neuronal systems underlying self-perception. The present paper reviews research implementing functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) to study the neural mechanisms of self-related information processing in persons with ASD. These experiments address the psychological aspects of self-representation associated with the appraisal of one’s own traits and of the symbolic, as well as physical, representation of self in response to the perception of one’s own name and face. Furthermore, results of a study that employed fMRI to assess the perception of changeability of personal traits across time among subjects with ASD are also included. The studies under review support the hypotheses of atypical neuronal mechanisms of cognitive self-representation and anomalous perception of social feedback in persons diagnosed with ASD.

Słowa kluczowe: spektrum autyzmu, ASD, reprezentacja Ja, neuronalne mechanizmy, przegląd literatury, kora czołowa, zakręt obręczy, fMRI, EEG / autism spectrum, self, self-representation, neuronal mechanisms, review, prefrontal cortex, cingulate gyrus, EEG

Adler N., Nadler B., Eviatar Z., Shamay-Tsoory S.G. (2010), The relationship between theory of mind and autobiographical memory in high-functioning autism and Asperger syndrome. Psychiatry Research, 178(1), 214–216.

Amsterdam B. (1972), Mirror self-image reactions before age two. Developmental Psychobiology: The Journal of the International Society for Developmental Psychobiology, 5(4), 297–305.

American Psychiatric Association (2013), Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: Author.

Banaji M.R., Prentice D.A. (1994), The self in social contexts. Annual Review of Psychology, 45(1), 297–332.

Bortfeld H., Morgan J.L., Golinkoff R.M., Rathbun K. (2005), Mommy and me: Familiar names help launch babies into speech-stream segmentation. Psychological Science, 16(4), 298–304.

Bosch G. (1970). Infantile autism. New York: Springer-Verlag.

Brezis R.S. (2015), Memory integration in the autobiographical narratives of individuals with autism. Frontiers in Human Neuroscience, 9, 76.

Buckner R.L., Andrews-Hanna J.R., Schacter D.L. (2008), The Brain’s Default Network: Anatomy, Function, and Relevance to Disease. Annals of the New York Academy of Sciences 1124 (1), 1–38.

Burrows C.A., Laird A. R., Uddin L.Q. (2016), Functional connectivity of brain regions for self- and othervaluation in children, adolescents and adults with autism. Developmental Science, 19(4), 564–580.

Cygan H.B., Marchewka A., Kotlewska I., Nowicka A. (2018), Neural Correlates of Reflection on Present and Past Selves in Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 1–11.

Cygan H.B., Tacikowski P., Ostaszewski P., Chojnicka I., Nowicka A. (2014), Neural correlates of own name and own face detection in autism spectrum disorder. PLoS One, 9(1), e86020.

D’Argembeau A., Feyers D., Majerus S., Collette F., Van der Linden M., Maquet P., Salmon E. (2008), Selfreflection across time: cortical midline structures differentiate between present and past selves. Social Cognitive and Affective Neuroscience, 3(3), 244–252.

Dennett D.C. (1991), Consciousness explained. Boston: Little, Brown and Company.

Dietrich D.E., Waller C., Johannes S., Wieringa B.M., Emrich H.M., Munte T.F. (2001), Differential effects of emotional content on event-related potentials in word recognition memory. Neuropsychobiology, 43, 96–101.

Gallagher S. (2000), Philosophical conceptions of the self: Implications for cognitive science. Trends in Cognitive Sciences, 4(1), 14–21.

Glezerman T. (2013), Autistic person’s sense of self. W: Autism and the Brain, 194. New York: Springer.

Gunji A., Inagaki M., Inoue Y., Takeshima Y., Kaga M. (2009), Event-related potentials of self-face recognition in children with pervasive developmental disorders. Brain and Development, 31, 139–147.

Horn A., Ostwald D., Reisert M., Blankenburg F. (2013), The structural-functional connectome and the default mode network of the human brain. NeuroImage, 102, 142–151.

Hu C., Di X., Eickhoff S. B., Zhang M., Peng K., Guo H., Sui J. (2016), Distinct and common aspects of physical and psychological self-representation in the brain: A meta-analysis of self-bias in facial and selfreferential judgements. Neuroscience & Biobehavioral Reviews, 61, 197–207.James W. (1983), The principles of psychology. Cambridge: Harvard University Press.

Kanner L. (1943), Autistic disturbances of affective contact. Nervous Child, 2, 217–250.

Kennedy D.P., Courchesne E. (2008), Functional abnormalities of the default network during self- and otherreflection in autism. Social Cognition and Affective Neuroscience, 3(2), 177–190.

Kim S.H., Lord C. (2012), New autism diagnostic interview-revised algorithms for toddlers and young preschoolers from 12 to 47 months of age. Journal of Autism and Developmental Disorders, 42(1), 82–93.

Knyazev G. (2013), EEG correlates of self-referential processing. Frontiers in Human Neuroscience, 7, 264. Lombardo M.V., Baron-Cohen S. (2011), The role of the self in mindblindness in autism. Consciousness and Cognition, 20(1), 130–140.

Lombardo M.V., Charkrabarti B., Bullmore E.T., Sadek S.A., Pasco G., Wheelwright S.J., Suckling J., Baron-Cohen S. (2010), Atypical neural self-representation in autism. Brain, 133(2), 611–624.

Luck S.J., Woodman G.F., Vogel E.K. (2000), Event-related potential studies of attention. Trends in Cognitive Sciences, 4(11), 432–440.

Lynch C.J., Uddin L.Q., Supekar K., Khouzam A., Phillips J., Menon V. (2013), Default mode network in childhood autism: posteromedial cortex heterogeneity and relationship with social deficits. Biological Psychiatry, 74 (3), 212–219.

Marsh H.W. (1997), The measurement of physical self-concept: A construct validation approach. W: K.R. Fox (eds.), The Physical Self: From Motivation to Well-Being, 27–58. Champaign, IL, US: Human Kinetics.

Marsh H.W. (2002), A multidimensional physical self-concept: A construct validity approach to theory, measurement and research. Psychology: The Journal of the Hellenic Psychological Society, 9, 459–493.

Mandel D.R., Jusczyk P.W., Pisoni D.B. (1995), Infants’ recognition of the sound patterns of their own names. Psychological Science, 6(5), 314–317.

McAdams D.P. (2001), The psychology of life stories. Review of General Psychology, 5(2), 100.

Miller M., Iosif A.M., Hill M., Young G.S., Schwichtenberg A.J., Ozonoff S. (2017), Response to name in infants developing autism spectrum disorder: A Prospective Study. The Journal of Pediatrics, 183, 141–146.

Morita T., Kosaka H., Saito D.N., Fujii T., Ishitobi M., Munesue T., Inohara T., Okazawa H., Kakigi R., Sadato N. (2016), Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders. Research in Autism Spectrum Disorders, 26, 16–32.

Nadig A.S., Ozonoff S., Young G.S., Rozga A., Sigman M., Rogers S.J. (2007), A prospective study of response to name in infants at risk for autism. Archives of Pediatrics & Adolescent Medicine, 161(4), 378–383.

Neisser U. (1993), The perceived self: Ecological and interpersonal sources of self-knowledge. Cambridge: Cambride University Press.

Nijhof A.D., Dhar M., Goris J., Brass M., Wiersema J.R. (2018), Atypical neural responding to hearing one’s own name in adults with ASD. Journal of Abnormal Psychology, 127(1), 129.

Nowicka A., Cygan H.B., Tacikowski P., Ostaszewski P., Kuś R. (2016), Name recognition in autism: EEG evidence of altered patterns of brain activity and connectivity. Molecular Autism, 7(1), 38.

Osterling J., Dawson G. (1994), Early recognition of children with autism: A study of first birthday home videotapes. Journal of Autism and Developmental Disorders, 24(3), 247–257.

Padmanabhan A., Lynch C. J., Schaer M., Menon V. (2017), The default mode network in autism. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2(6), 476–486.

Pfeifer J.H., Merchant J.S., Colich N.L., Hernandez L.M., Rudie J.D., Dapretto M. (2013), Neural and behavioral responses during self-evaluative processes differ in youth with and without autism. Journal of Autism and Developmental Disorders, 43(2), 272–285.

Polich J. (2007), Updating P300: An integrative theory of P3a and P3b. Clinical Neurophysiology, 118, 2128–2148.

Qin P., Northoff G. (2011), How is our self-related to midline regions and the default-mode network? Neuroimage, 57(3), 1221–1233.

Qin P., Liu Y., Shi J., Wang Y., Duncan N., Gong Q., Weng X., Northoff G. (2012), Dissociation between anterior and posterior cortical regions during self-specificity and familiarity: A combined fMRI-meta-analytic study. Human Brain Mapping, 33(1), 154–164.

Raichle M.E., MacLeod A.M., Snyder A.Z., Powers W.J., Gusnard D.A., Shulman G.L. (2001), A default mode of brain function. Proceedings of the National Academy of Sciences, 98(2), 676–682.

Rybak-Korneluk A., Wichowicz H.M., Żuk K., Dziurkowski M. (2016), Pamięć autobiograficzna i jej znaczenie w wybranych zaburzeniach psychicznych. Psychiatria Polska, 50, 959–972.

Sugiura M., Miyauchi C.M., Kotozaki Y., Akimoto Y., Nozawa T., Yomogida Y., Hanawa S., Yamamoto Y., Sakuma A., Nakagawa S., Kawashima R. (2014), Neural mechanism for mirrored self-face recognition. Cerebral Cortex, 25(9), 2806–2814.

Tacikowski P., Berger C.C., Ehrsson H.H. (2017), Dissociating the neural basis of conceptual self-awareness from perceptual awareness and unaware self-processing. Cerebral Cortex, 27(7), 3768–3781.

Tacikowski P., Brechmann A., Nowicka A. (2013), Cross-modal pattern of brain activations associated with the processing of self- and significant other’s name. Human Brain Mapping, 34, 2069–2077.

Tacikowski P., Cygan H.B., Nowicka A. (2014), Neural correlates of own and close-other’s name recognition: ERP evidence. Frontiers in Human Neuroscience, 8, 194.

Tacikowski P., Jednorog K., Marchewka A., Nowicka A. (2011), How multiple repetitions influence the processing of self-, famous and unknown names and faces: an ERP study. International Journal of Psychophysiology, 79, 219–230.

Uddin L.Q. (2011), The self in autism: an emerging view from neuroimaging. Neurocase, 17(3), 201–208.

Uddin L.Q., Davies M.S., Scott A.A., Zaidel E., Bookheimer S.Y., Iacoboni M., Dapretto M. (2008), Neural basis of self and other representation in autism: an FMRI study of self-face recognition. PloS One, 3(10), e3526.

Uddin L.Q., Supekar K., Lynch C.J., Khouzam A., Phillips J., Feinstein C., Ryali S., Menon V. (2013), Salience network-based classification and prediction of symptom severity in children with autism. JAMA Psychiatry, 70 (8), 869–879.

Washington S.D., Gordon E.M., Brar J., Warburton S., Sawyer A.T., Wolfe A., Mease-Ference E.R., Girton L ., Hailu A., Mbwana J., Gaillard W.D., Kalbfleisch M.L., VanMeter J.W. (2014), Dysmaturation of the default mode network in autism. Human Brain Mapping, 35(4), 1284–1296.

Woźniak M., Kourtis D., Knoblich G. (2018), Prioritization of arbitrary faces associated to self: An EEG study. PloS One, 13(1), e0190679.

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