The arguments for the use of enhanced and more effective techniques for managing problem situations emerging at different stages of enterprises’ adaptation to the new challenging market conditions are given in the paper. The approach to managing the problem situations arising at the stages of the enterprises’ pre-adaptation, co-adaptation and adaptation within production and economic organization is developed. The high inconsistency, low inconsistency and perfectly consistency zones between the enterprises’ interests within the production and economic organization under co-adaptation are identified. The equation for inconsistency level between companies reduction during their adaptation process is introduced. The ratio for assessing the relevance of situation to emerge is obtained.